On October 14, 2020, the 85th China International Pharmaceutical API/Intermediate/Packaging/Equipment Fair (referred to as API China API) opened at the Nanjing International Expo Center. Shangke Bio and Zhejiang Supor Pharmaceutical Co., Ltd. participated in the 2020 Nanjing API CHINA API Exhibition. Dr. Zhu, General Manager of Shangke Biology, made a special academic report on "NMN's Past, Present and Future" at the exhibition.

Exhibition crowd pictures

In this exhibition, Shangke Bio will display coenzyme NMN, NAD, NADH, NADP, NADPH, biological enzymes, APIs, intermediates and other products, and have in-depth exchanges with friends from all over the country.

During the exhibition, the 8th Vitamin Special Day of Health.com was successfully carried out. Dr. Zhu, General Manager of Shangke Biotechnology, was invited to participate in this event and gave a speech on the theme of "NMN's Past, Present and Future". The content of the speech was highly regarded by industry insiders. Recognition and high recognition of the enthusiastic response. . The anti-aging effect of NMN has been scientifically verified and supported by most real cases. The academic report of NMN on site has once again attracted the attention of numerous buyers and customers.

Academic report pictures

Dr. Zhu gave a speech from the development of NMN, and slowly uncovered the mystery of the anti-aging drug NMN: NMN is abbreviated as β-nicotinamide mononucleotide, which is the precursor of NAD+; relevant experimental conclusions published in a series of top international scientific journals prove that , believes that the content of NAD+ in the human body declines with age, leading to aging from the age of 30, with wrinkles, muscle relaxation, fat accumulation, and increased risk of heart disease, high blood pressure, stroke, diabetes, and Alzheimer's disease. The study found that when cells are low in NAD+, they respond by expressing more of the SLC12A8 transporter, allowing efficient absorption of NMN from the bloodstream, while the SLC12A8 transporter gene was found to be expressed in many tissues and in the gut The content in the tract is very high. In the intestine, NMN is rapidly absorbed from the small intestine within 2-3 minutes and converted into NAD+ within 10-30 minutes;

The anti-aging effect of NMN has been scientifically verified and supported by most real cases. At present, Japan has become a country that has legally approved NMN as a food raw material.

In January 2019, NMN had only 188 products on the entire network, and by the end of August 2020, the number of products on the entire domestic network had exceeded 2,962. There is a proliferation of products, lack of industry standards, and lack of consideration for safety and effectiveness. In addition, many NMN brands lack core technology, and the products are mixed.

The global anti-aging products market (including three categories of cosmetic care products, diet and pharmaceutical anti-aging products) was valued at US$250 billion in 2016 and is expected to grow at a CAGR of 5.8% to reach US$331.41 billion by 2021. North America is currently the leading region in the global anti-aging market, followed by Europe and Japan, and Asia Pacific is expected to be the fastest growing region in the world in the future. At present, the global raw material suppliers of NMN are mainly concentrated in China, and the production processes include chemical synthesis, chemical-enzymatic synthesis and whole-enzymatic method. Adequate clinical research on the relevant functions of NMN is the basis for future market growth, and legal compliance and localization are the key points for future market development. Coenzyme plays an indispensable role in the process of human physiological metabolism, and its products are widely used in the food and health product industry. In addition, coenzyme is the core raw material of green biopharmaceuticals.

Shangke Bio is an enterprise that realizes the industrial-scale production of coenzyme NMN/NAD/NADH/NADP/NADPH and other products through the whole enzyme catalysis technology, and has passed the ISO9001 quality management system certification, SELF GRAS (the US FDA evaluates the safety index of food additives) Safety certification and "acute oral toxicity test" authoritative certification have won a good reputation in the industry, and the products are exported to the world.