NMN alleviates radiation-induced intestinal fibrosis by modulating gut microbiota
Radiation-induced intestinal fibrosis is a common complication of long-term survivors after abdominal and pelvic radiotherapy. At present, there is no clinically available method to treat radiation-induced intestinal fibrosis. Studies have shown that nicotinamide mononucleotide (NMN) has the potential to regulate intestinal flora. Intestinal flora is a normal microorganism in human intestines, which can synthesize a variety of nutrients necessary for human growth and development. Once the intestinal flora is out of balance, it will cause a variety of diseases.
"Eating yourself" is healthier? The role of spermidine in health
Spermine is a substance existing in the human body. With the increase of age, the level of spermidine in the body decreases. Supplementing spermidine is helpful to self-cleaning in the human body. Old and redundant cellular components and harmful invaders such as viruses will be decomposed and recycled. Finally, it can improve, renew and purify cells from the root of cells, and then avoid various chronic diseases and metabolic diseases caused by cell damage.
Clinical study on human body: NMN can effectively reduce triglyceride level
Triglyceride (TG) is a kind of fat with a large content in human body. All organs and tissues of human body can use triglyceride to provide energy, and the liver can synthesize triglyceride and store it in the liver. If the triglyceride is increased, it means that the liver accumulates too much fat, which is fatty liver. Triglyceride is a kind of hyperlipidemia, and its main harm to human body is to cause atherosclerosis, blood vessel blockage and thrombosis. In addition, studies have shown that high triglycerides can also cause hypertension, gallstones, pancreatitis, Alzheimer's disease and so on.
A Narrative Review of Nicotinamide Adenine Dinucleotide (NAD)+ Intermediates Nicotinamide Riboside and Nicotinamide Mononucleotide for Keratinocyte Carcinoma Risk Reduction
Compared with NAM, oral NMN and NR can increase NAD+ level more efficiently and have better safety and tolerance, which is a potential treatment strategy for dermatologists to reduce the risk of keratinocyte cancer. However, it still needs a lot of clinical research data to verify its practical application in clinical treatment.
Molecular Metabolism : The therapeutic effect of NMN supplementation on polycystic ovary syndrome
In recent years, with the increase of unhealthy lifestyles and the increasing social pressure of women, the incidence rate of polycystic ovary syndrome ( PCOS ) has become more and more obvious. Foreign studies have shown that the incidence of polycystic ovary syndrome (PCOS) in women of childbearing age is as high as 6% -15 %, while in China, the proportion is as high as 6% -10 %.
Scientific research express | Spermidine can treat hypopigmentation
Hypopigmentation is a skin disease, mainly manifested by melanin reduction. Common symptoms include vitiligo, albinism and hypopigmentation after skin inflammation. At present, the main treatment for hypopigmentation is oral medicine, but oral medicine will cause skin atrophy, gastrointestinal discomfort and other adverse side effects. Therefore, it is necessary to develop a natural substance without side effects to treat hypopigmentation.
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